It depends on a few factors.
If spouses are also business partners and there has been infidelity, the marriage-related injury may need to be addressed through couples therapy or individual therapy on a separate track. Business Partners Counseling may still be useful for the business side of the relationship, as the partners may need to continue working together, make business decisions, or determine how to disentangle the business.
Business partnership work should not automatically replace marriage counseling. In most cases, infidelity in the personal relationship and business partnership issues need to be handled carefully, with appropriate professional boundaries.